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Anemia with thrombocytopenia indicates leukemia, systemic lupus erythematosus or aplastic anemia.
Hemolytic-uremic syndrome is characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia and acute renal injury.
Chronic inhalation abuse may also cause bone marrow depression resulting in leukopenia, anemia, thrombocytopenia , leukemia, and hemolysis.
Splenomegaly or giant hemangioma can result in thrombocytopenia because of platelet sequestration.
Purpura may be secondary to thrombocytopenia , platelet dysfunction, coagulation factor deficiency or vascular defect.
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